Methyl methacrylate-based prosthetic materials are widely used in dentistry due to
their favorable aesthetics, ease of processing, and cost-effectiveness. However, their inherent
brittleness increases the risk of fractures during clinical use. In response to this limitation,
current research efforts aim to improve not only the mechanical performance but also the
biological safety of these materials. This study aims to develop prosthetic composites with
enhanced antimicrobial resistance. For this purpose, polymeric materials were synthesized
based on a commercial prosthetic resin (Vertex) and oligomeric methyl methacrylate (OMM),
with zinc oxide (ZnO) incorporated as a functional additive to impart antimicrobial properties.
A combination of photochemical and thermal polymerization methods was employed to
produce composites with improved structural and biological performance. The resulting
materials were characterized using attenuated total reflectance Fourier-transform infrared
spectroscopy (ATR-FTIR), differential scanning calorimetry (DSC), and Shore D hardness
testing. Their antimicrobial efficacy was evaluated against Escherichia coli, Staphylococcus
aureus, and Candida albicans.
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