Chitosan scaffolds, films and microgranules for medical application — preparation and drug release studies

M. Mucha; I. Michalak; J. Balcerzak; M. Tylman

Published : 2012-10-30

Vol. 57 No. 10 (2012)

Chitosan scaffolds, films and microgranules for medical application — preparation and drug release studies

M. Mucha I. Michalak J. Balcerzak M. Tylman

Abstract

The paper presents various structural forms of chitosan for medical applications. These are films and microgranules for transdermal and oral application of active substances and porous scaffolds constituting support for the regenerating cells in bone tissue engineering. Tested porous systems were obtained by lyophilization or electrolytic method. Methods of sample preparation and the morphology analyses were presented. The influence of water on properties of transdermal systems and changes in release kinetics of active substances for microgranules and films under modification of their structures, were carried out.

Keywords

skafoldy ; mikrogranule ; kinetyka uwalniania leku ; liofilizacja ; elektroliza scaffolds ; microgranules ; kinetics of drug release ; lyophilization ; electrolysis

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Mucha, M., Michalak, I., Balcerzak, J., & Tylman, M. (2012). Chitosan scaffolds, films and microgranules for medical application — preparation and drug release studies. Polimery, 57(10), 714–721. Retrieved from https://polimery.ichp.vot.pl/index.php/p/article/view/867

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